The brain, spinal cord, neurons and nerves

Organisms (Interaction and interdependence) · Integration of body systems · note 2 of 9

The brain, spinal cord, neurons and nervesSpec C3.1.4, C3.1.5, C3.1.6, C3.1.7, C3.1.8

In short

The brain is the central information integration organ: it processes information combined from several inputs and is the site of learning and memory. The spinal cord is an integrating centre for unconscious processes. Sensory neurons carry messages from receptor cells to the central nervous system, motor neurons carry impulses to muscles, and nerves are bundles of both.

The brain as the central integration organ

The brain receives impulses from many receptors at once, for example the eyes, ears and skin. It processes information combined from several inputs, compares it with stored information, and decides on a response. The brain is also the organ of learning and memory: experiences cause lasting changes in the connections between neurons, so information can be stored and recalled to modify later behaviour.

The spinal cord and unconscious processes

The spinal cord is an integrating centre for unconscious processes, such as reflexes. Conscious processes are those we are aware of and can control voluntarily, such as deciding to pick up a cup; they are coordinated by the cerebral hemispheres. Unconscious processes happen without awareness or deliberate decision, such as withdrawing a hand from a sharp object; they can be coordinated by the spinal cord without involving the brain.

In a transverse section of the spinal cord, the central grey matter contains cell bodies of neurons, interneurons and synapses; the outer white matter contains myelinated nerve fibres that carry impulses up and down the cord.

Sensory and motor neurons

  • Sensory neurons convey messages from receptor cells to the central nervous system (CNS): input to the spinal cord and to the cerebral hemispheres.
  • Motor neurons carry output from the cerebral hemispheres (and the spinal cord) to muscles, which are stimulated to contract.

Nerves

A nerve is a bundle of nerve fibres (axons) of both sensory and motor neurons, surrounded by a protective sheath of connective tissue. A transverse section of a nerve shows many fibres; some are myelinated (surrounded by a myelin sheath, which speeds conduction) and some are unmyelinated. Blood vessels supply the fibres.

Side view of the human brain with the cerebral cortex, cerebellum, medulla and spinal cord labelled. (opens full size in a new tab)
The cerebral cortex (outer layer of the cerebral hemispheres) integrates conscious processes, the cerebellum coordinates movement and the medulla controls heart rate and ventilation.
Transverse section of a nerve showing the protective sheath of connective tissue, bundles of nerve fibres, myelinated nerve fibres with a ring of myelin sheath, small unmyelinated nerve fibres and a blood vessel. (opens full size in a new tab)
Transverse section of a nerve: a nerve contains fibres of both sensory and motor neurons, some myelinated and some unmyelinated, inside a protective sheath.

Written and checked against the IB Biology HL specification · Updated October 2026

Frequently asked questions

What is the difference between the nervous system and the endocrine system?

The nervous system sends electrical impulses along neurons to specific cells, giving fast, short-lived responses. The endocrine system secretes hormones into the blood, which carries them to all parts of the body, but only target cells with receptors respond. Hormonal responses are slower but usually longer lasting.

What happens in a pain reflex arc?

A free nerve ending in the hand detects pain and a sensory neuron carries impulses to the spinal cord. In the grey matter it synapses with a single interneuron, which passes the impulse to a motor neuron. The motor neuron makes a skeletal muscle contract, pulling the hand away before the pain is felt consciously.

How is heart rate controlled during exercise?

During exercise, blood carbon dioxide rises and pH falls. Chemoreceptors in the aortic and carotid bodies detect this and signal the medulla. The medulla sends impulses along a sympathetic nerve to the heart, increasing heart rate and stroke volume. Baroreceptors detect blood pressure and help return it to normal by negative feedback.

All 5 questions on Integration of body systems