Clock it with SCIBook a tutor

Chemical digestion and digestive enzymes

Human nutrition · Chemical digestion · note 1 of 2

Chemical digestion and digestive enzymesSpec 7.4.1, 7.4.2, 7.4.3, 7.4.4

Chemical digestion is the breakdown of large insoluble molecules into small soluble molecules. It is carried out by enzymes.

The small soluble molecules made by chemical digestion can be absorbed into the blood. Large insoluble molecules cannot pass through the wall of the gut.

Digestive enzymes
EnzymeBreaks downIntoSecreted by (made in)Acts in
AmylaseStarchSimple reducing sugarsSalivary glands and pancreasMouth and small intestine
ProteaseProteinAmino acidsStomach and pancreasStomach and small intestine
LipaseFats and oilsFatty acids and glycerolPancreasSmall intestine
starch → simple reducing sugars (amylase)
protein → amino acids (proteases)
fats and oils → fatty acids + glycerol (lipase)

Enzymes made in the pancreas flow into the duodenum, so the pancreas is where they are secreted but the small intestine is where they act. Quote both places if a question asks where an enzyme is secreted and where it acts.

Exam tip:

Learn each enzyme as a set of three: substrate, product, and where it is secreted and acts. Mark schemes ask for the product by name.