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Meiosis

Inheritance · Mitosis and meiosis · note 3 of 3

Spec 17.3.1, 17.3.2
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MeiosisSpec 17.3.1, 17.3.2

In short

Meiosis is a reduction division that halves the chromosome number from diploid to haploid, producing gametes that are genetically different from each other and from the parent cell. It takes place in the testes and ovaries. In humans, gametes with 23 chromosomes are made from cells with 46, so fertilisation restores 46 in the zygote.

Meiosis is involved in the production of gametes. It takes place in the reproductive organs (the testes and ovaries in humans).

Meiosis is a reduction division. The chromosome number is halved from diploid to haploid. It results in cells that are genetically different from each other and from the parent cell.

A diploid parent cell divides by meiosis to make haploid gametes; fertilisation joins two gametes to restore the diploid number in the zygote. (opens full size in a new tab)
Meiosis halves the chromosome number in gametes; fertilisation restores the full number, then mitosis builds the embryo.

In humans, meiosis makes gametes with 23 chromosomes from a cell with 46 chromosomes. When a sperm fertilises an egg, the full number of 46 chromosomes is restored in the zygote. If gametes were diploid, the chromosome number would double in every generation.

Mitosis compared with meiosis
MitosisMeiosis
Number of daughter cells24
Chromosome number in daughter cellssame as parent (diploid)half of parent (haploid)
Geneticallyidentical to the parentdifferent from each other and the parent
Used forgrowth, repair, replacement, asexual reproductionproduction of gametes
Exam tip:

You do not need the stages of meiosis. Learn the keywords: gametes, reduction division, diploid to haploid, genetically different.

Quick check

  1. Supplement Define mitosis.

    Show answer

    Nuclear division giving rise to genetically identical cells.

  2. Supplement State four roles of mitosis.

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    Growth, repair of damaged tissues, replacement of cells, asexual reproduction.

  3. Supplement What happens to the chromosomes before mitosis?

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    They are copied exactly (replicated).

  4. Supplement What is a stem cell?

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    An unspecialised cell that divides by mitosis to produce daughter cells that can become specialised.

  5. Supplement What happens to the chromosome number in meiosis?

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    It is halved, from diploid to haploid.

Written and checked against the Cambridge IGCSE Biology (0610) specification · Updated October 2026

Frequently asked questions

What is the difference between mitosis and meiosis?

Mitosis produces two genetically identical diploid cells, while meiosis produces four genetically different haploid cells. Mitosis is used for growth, repair, cell replacement and asexual reproduction. Meiosis is a reduction division used to make gametes in the testes and ovaries, halving the chromosome number from diploid to haploid.

Why is meiosis important for sexual reproduction?

Meiosis is important because it halves the chromosome number, so gametes are haploid. When a sperm fertilises an egg, the full diploid number is restored in the zygote: 46 chromosomes in humans. If gametes were diploid, the chromosome number would double in every generation. Meiosis also makes gametes genetically different.

Why are stem cells useful?

Stem cells are useful because they are unspecialised cells that divide by mitosis to produce daughter cells that can become specialised, such as red blood cells or nerve cells. Some daughter cells stay as stem cells, so the supply is not used up. They become specialised when only some of their genes are expressed.

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