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Protecting the breathing system

Gas exchange in humans · Gas exchange in humans · note 6 of 6

Spec 11.1.11
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Protecting the breathing systemSpec 11.1.11

In short

The breathing system is protected by goblet cells and ciliated cells lining the trachea and bronchi. Goblet cells make and release mucus, a sticky liquid that traps pathogens and particles from the air. Ciliated cells have cilia that beat to move the mucus up and away from the lungs towards the throat, where it is swallowed.

The air you breathe in contains dust and particles, and microorganisms that cause disease (pathogens). The lining of the trachea and bronchi has two types of cell, goblet cells and ciliated cells, that protect the lungs from these.

Cells that protect the breathing system
Cell or substanceRole
Goblet cellsMake and release mucus
MucusSticky liquid that traps pathogens and particles from the air
Ciliated cellsHave tiny hair-like projections called cilia that beat to move the mucus, with the trapped pathogens and particles, up and away from the lungs towards the throat, where it is swallowed
Section through the lining of the trachea: ciliated cells with cilia and goblet cells releasing mucus, a layer of mucus with trapped particles and pathogens, and an arrow showing the cilia moving the mucus up towards the throat. (opens full size in a new tab)
Goblet cells make mucus that traps particles and pathogens, and cilia beat to move it up towards the throat.
Exam tip:

A full answer links the three parts: goblet cells make mucus, mucus traps the pathogens and particles, and cilia move the mucus away from the lungs.

Quick check

  1. Name the tubes that carry air into each lung.

    Show answer

    Bronchi.

  2. State the four features of a gas exchange surface in humans.

    Show answer

    Large surface area, thin surface, good blood supply and good ventilation with air.

  3. Which gas turns limewater cloudy?

    Show answer

    Carbon dioxide.

  4. Supplement What happens to the pressure in the thorax when the diaphragm contracts?

    Show answer

    It decreases, because the volume of the thorax increases.

  5. Supplement State the function of cartilage in the trachea.

    Show answer

    It supports the trachea and keeps it open.

Written and checked against the Cambridge IGCSE Biology (0610) specification · Updated October 2026

Frequently asked questions

How are alveoli adapted for gas exchange?

Alveoli are adapted for gas exchange by having a large surface area, from millions of alveoli, and thin walls one cell thick, giving a short diffusion distance. A network of capillaries around each alveolus gives a good blood supply, and ventilation brings fresh air. Both keep a steep concentration gradient, so diffusion is fast.

How does the diaphragm help you breathe in?

Supplement When you breathe in, the diaphragm muscles contract, so the diaphragm moves down and flattens. At the same time the external intercostal muscles contract and lift the ribs up and out. The volume of the thorax increases and the pressure falls below the air pressure outside, so air moves into the lungs.

Why does expired air contain more carbon dioxide than inspired air?

Supplement Expired air contains more carbon dioxide because body cells produce carbon dioxide in respiration. It is carried to the lungs in the blood and diffuses into the alveoli, so expired air has about 4% carbon dioxide compared with about 0.04% in inspired air. Expired air also contains less oxygen and more water vapour.

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