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Digesting starch and protein in detail

Human nutrition · Chemical digestion · note 2 of 2

Spec 7.4.6, 7.4.7
Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean
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Digesting starch and protein in detailSpec 7.4.6, 7.4.7

Starch

  1. Amylase from the salivary glands and the pancreas breaks starch down to maltose.
  2. Maltase breaks maltose down to glucose. Maltase is on the membranes of the epithelium lining the small intestine.
  3. Glucose is small and soluble, so it can be absorbed into the blood.
starch → maltose (amylase); maltose → glucose (maltase)

Protein

Two proteases
ProteaseWhere it worksConditions
PepsinStomachAcidic, because of the hydrochloric acid in gastric juice
TrypsinSmall intestineAlkaline, because of the bile mixed with the food

Each enzyme has an optimum pH. Pepsin works best in acid and trypsin works best in alkali. Both are proteases, so both break down protein.

Flow diagram of digestion: mouth (amylase from the salivary glands: starch to maltose; neutral), stomach (pepsin breaks down protein; hydrochloric acid; acidic), duodenum (bile is alkaline and neutralises the acid; trypsin, amylase and lipase from the pancreas; alkaline), ileum (maltase on the membranes of the epithelium: maltose to glucose; alkaline). (opens full size in a new tab)
Pepsin works in the acidic stomach; trypsin works in the alkaline small intestine, where bile has neutralised the acid.
Common mistake:

Amylase does not make glucose directly. It makes maltose, and maltase then makes glucose. Link each enzyme to its own product.

Quick check

  1. What is chemical digestion?

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    The breakdown of large insoluble molecules into small soluble molecules.

  2. What does lipase break down fats and oils into?

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    Fatty acids and glycerol.

  3. Where is amylase secreted?

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    Salivary glands and pancreas.

  4. Supplement Which enzyme breaks maltose down to glucose, and where is it found?

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    Maltase, on the membranes of the epithelium lining the small intestine.

  5. Supplement Why does trypsin work in the small intestine but pepsin does not?

    Show answer

    Trypsin works in alkaline conditions and pepsin works in acidic conditions; bile makes the small intestine alkaline.

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