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The breathing system

Gas exchange in humans · Gas exchange in humans · note 1 of 6

The breathing systemSpec 11.1.2, 11.1.6, 11.1.7

In short

The breathing system carries air through the larynx and trachea into two bronchi, then into smaller bronchioles that end in air sacs called alveoli, where gas exchange happens. The lungs sit in the thorax, protected by the ribs. The intercostal muscles move the ribs, and the diaphragm, a sheet of muscle, forms the floor of the thorax.

Air enters the body through the nose or mouth and travels to the lungs along a series of tubes. The lungs sit inside the thorax (chest), protected by the ribs. The diaphragm forms the floor of the thorax.

  1. Air passes through the larynx (voice box) into the trachea (windpipe).
  2. The trachea divides into two bronchi (singular: bronchus), one to each lung.
  3. Each bronchus branches into many smaller tubes called bronchioles.
  4. The bronchioles end in tiny air sacs called alveoli (singular: alveolus).
  5. Each alveolus is surrounded by a network of capillaries, where gas exchange happens.
Front view of the human breathing system with labels for the larynx, trachea, bronchi, bronchioles, lung, ribs, intercostal muscles and diaphragm, and an enlarged inset of alveoli surrounded by a capillary network. (opens full size in a new tab)
Air passes through the larynx, trachea, bronchi and bronchioles to the alveoli, which are surrounded by a network of capillaries.
Parts of the breathing system
PartDescription or function
LungsOrgans in the thorax where gas exchange takes place
RibsBones that protect the lungs and move to change the volume of the thorax
Intercostal musclesMuscles between the ribs that move the ribs
DiaphragmSheet of muscle below the lungs that separates the thorax from the abdomen
LarynxVoice box at the top of the trachea
TracheaWindpipe: carries air to the bronchi
BronchiTwo tubes that carry air into the lungs
BronchiolesSmall tubes that carry air to the alveoli
AlveoliAir sacs where oxygen and carbon dioxide are exchanged with the blood in the capillaries
Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean

Intercostal muscles

Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean

There are two sets of intercostal muscles between each pair of ribs. The external intercostal muscles are on the outside. The internal intercostal muscles are on the inside, underneath them. The two sets work against each other to move the ribs.

Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean

Cartilage in the trachea

Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean

The wall of the trachea contains C-shaped rings of cartilage. The function of the cartilage is to support the trachea and keep it open, so air can always flow through it, even when the pressure inside falls as you breathe in.

Exam tip:

Spell bronchi (plural, two tubes) and bronchioles (the small tubes) carefully. They are often mixed up, and the mark is lost if the wrong one is written.

Written and checked against the Cambridge IGCSE Biology (0610) specification · Updated October 2026

Frequently asked questions

How are alveoli adapted for gas exchange?

Alveoli are adapted for gas exchange by having a large surface area, from millions of alveoli, and thin walls one cell thick, giving a short diffusion distance. A network of capillaries around each alveolus gives a good blood supply, and ventilation brings fresh air. Both keep a steep concentration gradient, so diffusion is fast.

How does the diaphragm help you breathe in?

Supplement When you breathe in, the diaphragm muscles contract, so the diaphragm moves down and flattens. At the same time the external intercostal muscles contract and lift the ribs up and out. The volume of the thorax increases and the pressure falls below the air pressure outside, so air moves into the lungs.

Why does expired air contain more carbon dioxide than inspired air?

Supplement Expired air contains more carbon dioxide because body cells produce carbon dioxide in respiration. It is carried to the lungs in the blood and diffuses into the alveoli, so expired air has about 4% carbon dioxide compared with about 0.04% in inspired air. Expired air also contains less oxygen and more water vapour.

All 5 questions on Gas exchange in humans