From base order to protein shapeSpec 3.7B
A gene is a section of DNA that codes for a specific protein. Proteins are made of chains of amino acids. The order of bases in a section of DNA decides the order of amino acids in the protein.
- The sequence of bases in the gene decides the order of amino acids.
- The chain of amino acids folds up.
- The way the chain folds depends on the order of the amino acids, so it produces a specifically shaped protein.
The shape of a protein matters because it decides what the protein can do. For example, an enzyme has an active site with a shape that fits its substrate. A different order of bases would give a different order of amino acids, a differently folded protein and so a different shape.