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Monohybrid inheritance

Genetics · Inheritance · note 4 of 8

Monohybrid inheritanceSpec 3.14

Monohybrid inheritance is the inheritance of a characteristic controlled by a single gene. You can show it using a genetic diagram, a Punnett square or a family pedigree.

  1. Choose letters for the alleles: a capital for dominant, lower case for recessive.
  2. Write the genotypes of the parents.
  3. Write the possible gametes from each parent. Each gamete has one allele.
  4. Combine the gametes in a Punnett square to show the possible genotypes of the offspring.
  5. Write the phenotype for each genotype.

Crossing two heterozygous pea plants

Tall (T) is dominant to short (t). Two heterozygous tall plants (Tt) are crossed. Show the possible offspring.

  1. Parent genotypes: Tt and Tt.
  2. Gametes: T or t from each parent.
  3. Punnett square: top row (gametes from parent 1) T and t; side column (gametes from parent 2) T and t. The four boxes are TT, Tt, Tt and tt.
  4. Phenotypes: TT, Tt and Tt are tall; tt is short.

Answer: Offspring genotypes: 1 TT : 2 Tt : 1 tt. Phenotypes: 3 tall : 1 short.

Punnett square for Tt × Tt: gametes T and t from each parent give offspring TT, Tt, Tt (tall) and tt (short).Tap to enlarge
Tt × Tt gives 3 tall : 1 short (1 TT : 2 Tt : 1 tt).

Family pedigrees

A family pedigree (family tree) shows who in a family has a characteristic. Squares are usually males and circles are females. Shaded shapes show people with the characteristic. A horizontal line joins the parents and a vertical line leads down to their children.

  • If two parents who do not have a characteristic have a child who does, the characteristic is recessive. Both parents must be carriers, heterozygous with one copy of the recessive allele.
  • If two parents who both have a characteristic have a child who does not, the characteristic is dominant. Both parents must be heterozygous.
Three-generation family pedigree with squares for males and circles for females: an affected grandmother (rr) and her carrier son (Rr) and his unaffected carrier partner (Rr) have an affected daughter (rr) and two unaffected children (RR or Rr).Tap to enlarge
Two unaffected parents with an affected daughter: the characteristic is recessive and both parents are carriers (Rr).