Clock it with SCIBook a tutor

Calculating and analysing outcomes

Genetics · Inheritance · note 6 of 8

Calculating and analysing outcomesSpec 3.16

You need to calculate and analyse the outcomes of monohybrid crosses and pedigrees for dominant and recessive traits. Outcomes can be given as a ratio, a probability or a percentage.

Ways of giving the same outcome (Tt × Tt)
OutcomeBoxes out of 4ProbabilityPercentage
Short plant (tt)11/4 or 0.2525%
Tall plant (TT or Tt)33/4 or 0.7575%

As a ratio, this is 3 tall : 1 short. A 3 : 1 ratio means 1 in 4 offspring are short, not 1 in 3.

Probability for a recessive disorder

A disorder is caused by a recessive allele (f). Two parents do not have the disorder but both are carriers (Ff). What is the probability that their child has the disorder?

  1. Gametes from each parent: F or f.
  2. Possible offspring: FF, Ff, Ff and ff.
  3. Only ff has the disorder. That is 1 out of 4 equally likely outcomes.

Answer: Probability = 1/4 = 0.25 = 25%.

Each child is an independent event. If the first child has the disorder, the probability for the next child is still 1 in 4. Probabilities describe chance. They do not guarantee the actual numbers in a family.