Integration of body systems — IB Diploma Biology SL

IB Biology C3.1: system integration, nerves and hormones, the brain and spinal cord, reflex arcs and feedback control.

Spec C3.1Organisms (Interaction and interdependence), subtopic 1 of 2

Revision notes

6 short notes, in the order of the specification. Each one in short:

  1. System integration is the coordination of the component parts of a system so that they collectively perform an overall function. In a multicellular organism, cells, tissues, organs and body systems form a hierarchy of subsystems. Nerves and hormones send signals between organs, and the blood transports materials and energy between them, giving emergent properties.

  2. The brain is the central information integration organ: it processes information combined from several inputs and is the site of learning and memory. The spinal cord is an integrating centre for unconscious processes. Sensory neurons carry messages from receptor cells to the central nervous system, motor neurons carry impulses to muscles, and nerves are bundles of both.

  3. A pain reflex arc is an involuntary response with skeletal muscle as the effector. A free nerve ending of a sensory neuron in the hand detects pain, the impulse passes to a single interneuron in the grey matter of the spinal cord, then to a motor neuron that makes a muscle contract. The cerebellum coordinates skeletal muscle contraction and balance.

  4. Melatonin is a hormone secreted by the pineal gland in a diurnal pattern: secretion rises in the evening darkness and falls in the morning light, helping to establish a cycle of sleeping and waking. Epinephrine from the adrenal glands prepares the body for vigorous activity. The hypothalamus and pituitary gland control the rest of the endocrine system.

  5. Heart rate and ventilation rate are controlled by negative feedback. Baroreceptors monitor blood pressure and chemoreceptors monitor blood pH and the concentrations of oxygen and carbon dioxide. The medulla coordinates the response, sending nerve impulses to the heart to change heart rate and stroke volume, and to the diaphragm and intercostal muscles to change ventilation rate.

  6. Peristalsis is the wave of muscle contraction that moves food along the gut. Swallowing of food and egestion of faeces are under voluntary control by the central nervous system, but peristalsis between these points is under involuntary control by the enteric nervous system, a network of neurons in the gut wall that coordinates the passage of material.

Start reading

Exam questions

5 exam-style questions (19 marks), each with its mark scheme.

Answer the questions

Flashcards

19 cards: flip them, mark what you knew, and practise the rest.

Practise the cards

Mind map

The whole of organisms (interaction and interdependence) on one page, so you can see where this subtopic fits.

Open the mind map

Print it

Free PDFs to print or save.

Quick check questions

  1. What is meant by an emergent property, and what example does the IB guide use?

    Show answer

    A property of the whole organism that arises from integration of its parts; a cheetah becomes an effective predator through integration of its body systems.

  2. Which part of the nervous system is an integrating centre for unconscious processes?

    Show answer

    The spinal cord.

  3. Where are baroreceptors located?

    Show answer

    In the walls of the aorta (aortic arch) and the carotid arteries.

  4. Which gland secretes melatonin, and when is secretion highest?

    Show answer

    The pineal gland; secretion is highest at night, in darkness.

Frequently asked questions

What is the difference between the nervous system and the endocrine system?

The nervous system sends electrical impulses along neurons to specific cells, giving fast, short-lived responses. The endocrine system secretes hormones into the blood, which carries them to all parts of the body, but only target cells with receptors respond. Hormonal responses are slower but usually longer lasting.

What happens in a pain reflex arc?

A free nerve ending in the hand detects pain and a sensory neuron carries impulses to the spinal cord. In the grey matter it synapses with a single interneuron, which passes the impulse to a motor neuron. The motor neuron makes a skeletal muscle contract, pulling the hand away before the pain is felt consciously.

How is heart rate controlled during exercise?

During exercise, blood carbon dioxide rises and pH falls. Chemoreceptors in the aortic and carotid bodies detect this and signal the medulla. The medulla sends impulses along a sympathetic nerve to the heart, increasing heart rate and stroke volume. Baroreceptors detect blood pressure and help return it to normal by negative feedback.

How does melatonin control sleep?

Melatonin is secreted by the pineal gland in a diurnal pattern. Secretion rises in the evening as it gets dark and stays high at night, promoting sleep. Light in the morning inhibits secretion, so levels fall and the person wakes. This helps establish a regular cycle of sleeping and waking as part of circadian rhythms.

Written and checked against the IB Biology SL specification · Updated October 2026