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The effect of lifestyle on disease

Organisation · Animal tissues, organs and organ systems · note 17 of 20

The effect of lifestyle on diseaseSpec 4.2.2.6

You need to be able to explain the effect of lifestyle factors including diet, alcohol and smoking on the incidence of non-communicable diseases.

Lifestyle factors and disease
Risk factorEffect
Diet, smoking and exercise: cardiovascular diseaseA diet high in saturated fat can raise blood cholesterol, which leads to fatty deposits in the arteries. Chemicals in tobacco smoke damage the artery lining and raise blood pressure, and carbon monoxide reduces the oxygen the blood can carry. Regular exercise reduces the risk
Obesity: Type 2 diabetesObesity is a risk factor for Type 2 diabetes
Alcohol: liver and brainDrinking too much alcohol over a long time damages the liver. Alcohol also affects brain function, for example slowing reactions, and long-term heavy drinking can damage the brain
Smoking: lung disease and lung cancerSmoking damages the lungs and airways, causing lung disease. Tar in tobacco smoke contains chemicals that cause lung cancer
Smoking and alcohol: unborn babiesSmoking in pregnancy can cause low birth weight and premature birth. Alcohol in pregnancy can damage the baby's development, including the brain
Carcinogens (including ionising radiation): cancerA carcinogen is a substance or type of radiation that can cause cancer, such as chemicals in tobacco smoke. Ionising radiation, such as X-rays and gamma rays, can damage the DNA in cells

Because lifestyles differ, the incidence of these diseases is different in different places. Diseases linked to diet and obesity, for example, are more common in places where people eat more high-energy food and take less exercise. This is true at local, national and global levels.