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Adrenaline, thyroxine and negative feedback

Homeostasis and response · Hormonal coordination in humans · note 11 of 11

Spec 4.5.3.7Higher tierDownload these notes (PDF)12 pages

Adrenaline, thyroxine and negative feedbackSpec 4.5.3.7

Adrenaline

Adrenaline is produced by the adrenal glands in times of fear or stress. It increases the heart rate and boosts the delivery of oxygen and glucose to the brain and muscles, preparing the body for ‘flight or fight’.

Thyroxine

Thyroxine from the thyroid gland stimulates the basal metabolic rate. It plays an important role in growth and development.

Negative feedback

Thyroxine levels are controlled by negative feedback. If the thyroxine level in the blood becomes too high, less thyroxine is released, so the level falls. If it becomes too low, more is released, so the level rises. A change in the level is reversed to bring it back to normal.

Negative feedback for thyroxine: if the thyroxine level is too high, less thyroxine is released by the thyroid gland and the level falls to normal; if it is too low, more is released and the level rises to normal.Tap to enlarge
Thyroxine levels are controlled by negative feedback: the response reverses the change.

Quick check

  1. What is a hormone?

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    A chemical secreted by a gland directly into the bloodstream, which acts on a target organ.

  2. Which hormone lowers blood glucose concentration, and where is it made?

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    Insulin, made in the pancreas.

  3. Compare the cause of Type 1 and Type 2 diabetes.

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    Type 1: the pancreas fails to produce enough insulin. Type 2: the body cells no longer respond to insulin.

  4. Name the hormone that causes the release of the egg.

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    Luteinising hormone (LH).

  5. Give two non-hormonal methods of contraception.

    Show answer

    Any two of: condoms, diaphragms, spermicidal agents, abstaining, surgical sterilisation (non-hormonal intrauterine devices also accepted).

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