Clock it with SCIBook a tutor

Genetic engineering

Inheritance, variation and evolution · Variation and evolution · note 4 of 5

Genetic engineeringSpec 4.6.2.4

Genetic engineering
A process which involves modifying the genome of an organism by introducing a gene from another organism to give a desired characteristic.

In genetic engineering, genes from the chromosomes of humans and other organisms can be 'cut out' and transferred to cells of other organisms.

  • Plant crops have been genetically engineered to be resistant to diseases or to produce bigger, better fruits.
  • Bacterial cells have been genetically engineered to produce useful substances such as human insulin to treat diabetes.

Crops that have had their genes modified in this way are called genetically modified (GM) crops. GM crops include ones that are resistant to insect attack or to herbicides. GM crops generally show increased yields.

Benefits, risks and objections

Genetic engineering in agriculture and medicine
Potential benefitsPotential risks and objections
AgricultureIncreased yields; resistance to insects, herbicides or disease; bigger, better fruitsEffects on populations of wild flowers and insects; some people feel the effects of eating GM crops on human health have not been fully explored
MedicineBacteria can make useful substances such as human insulin; research is exploring genetic modification to overcome some inherited disordersSome people object to altering the genes of organisms, especially humans; long-term effects may not be known

Some people have objections to genetic engineering, even though it has huge potential benefits.

Higher tier

The main steps in genetic engineering

Higher tier
  1. Enzymes are used to isolate the required gene.
  2. The gene is inserted into a vector, usually a bacterial plasmid or a virus.
  3. The vector is used to insert the gene into the required cells.
  4. Genes are transferred to the cells of animals, plants or microorganisms at an early stage in their development, so that they develop with the desired characteristics.
Higher tier
Higher tier
Flow diagram of genetic engineering: enzymes cut the human insulin gene out of human DNA and cut open a bacterial plasmid, the gene is inserted into the plasmid (the vector), the plasmid is taken up by a bacterium, and the bacteria multiply and make human insulin.Tap to enlarge
Enzymes isolate the gene, a plasmid (vector) carries it into a bacterium, and the bacteria multiply and make human insulin.