Specialised mammalian gametesSpec 3.11
In short
Mammalian gametes are specialised for fertilisation. A sperm has a flagellum for swimming, many mitochondria in the midpiece to make ATP, and an acrosome containing digestive enzymes. An egg cell is large with food stores in its cytoplasm, has a zona pellucida around it, and cortical granules just under its surface membrane.
| Gamete | Feature | Function |
|---|---|---|
| Sperm | Haploid nucleus in the head | Carries the paternal genes |
| Sperm | Acrosome at the front of the head: a modified lysosome containing hydrolytic (digestive) enzymes | Releases enzymes to digest a path through the zona pellucida |
| Sperm | Midpiece with many mitochondria, wound round the base of the flagellum | Produces ATP by aerobic respiration for swimming |
| Sperm | Long flagellum (tail) containing microtubules | Moves the sperm towards the egg |
| Egg cell | Large cell with a haploid nucleus and a lot of cytoplasm, containing food stores | Supplies nutrients to the early embryo until it implants |
| Egg cell | Zona pellucida: a jelly-like layer of glycoproteins outside the cell surface membrane | Contains receptors that bind sperm of the same species; protects the egg; hardens after fertilisation |
| Egg cell | Cortical granules: vesicles just under the cell surface membrane, containing enzymes | Released after fertilisation to prevent other sperm entering (cortical reaction) |
The egg is surrounded by a layer of follicle cells, which the sperm must pass. Both gametes are haploid, so when the nuclei fuse, the diploid number is restored.
Written and checked against the Edexcel International AS Level Biology (XBI11) specification · Updated October 2026