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Platelets and blood clotting

Structure and functions in living organisms · Blood and the immune system · note 4 of 4

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Platelets and blood clottingSpec 2.64B

When a blood vessel is cut, the blood must clot. Platelets are small fragments of cells that take part in this. Clotting prevents blood loss and stops micro-organisms entering the body through the wound.

  1. Platelets collect at the cut and release chemicals.
  2. These chemicals cause the soluble protein fibrinogen in the plasma to change into insoluble fibrin.
  3. Fibrin forms a mesh of fibres across the wound.
  4. The mesh traps red blood cells and forms a clot.
  5. The clot dries to form a scab, which seals the wound while the skin underneath repairs.
Four stages of a cut in the skin: platelets collect at the cut as blood flows out of a blood vessel; platelets release chemicals that change soluble fibrinogen into insoluble fibrin threads; a fibrin mesh traps red blood cells to form a clot; the clot dries to form a scab with new skin forming underneath. (opens full size in a new tab)
Platelets trigger the change of fibrinogen to fibrin. The fibrin mesh traps red blood cells to form a clot, which dries to a scab.
Exam tip:

Give two reasons why clotting matters: it stops blood loss and it stops pathogens (micro-organisms) entering the body.

Quick check

  1. Name the four components of blood.

    Show answer

    Red blood cells, white blood cells, platelets and plasma.

  2. Give three adaptations of a red blood cell for carrying oxygen.

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    Biconcave shape, no nucleus, contains haemoglobin.

  3. How do phagocytes destroy pathogens?

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    They ingest (engulf) them.

  4. What do lymphocytes release?

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    Antibodies that are specific to the pathogen.

  5. Biology only What do memory cells allow after vaccination?

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    Antibody production that is sooner, faster and in greater quantity if the pathogen enters again.

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