AQA GCSE Combined Science: Trilogy specification checklist
All 71 spec points of 8464 that our notes cover, topic by topic. Rate each one red, amber or green as you revise, and follow the link to the note when you need it.
AQA GCSE Combined Science: Trilogy (8464) specification checklist · clockitwithsci.com
The numbers are AQA's own spec references for 8464. Higher tier: only on the Higher tier papers. Foundation students can skip it. Teachers: you are welcome to print this checklist and share it with your classes.
Biology Paper 11 hour 15 minutes · 70 marks
1Cell biology
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.1.1.1 | Eukaryotes and prokaryotes | |||
| 4.1.1.2 | Animal and plant cells; Required practical 1: using a light microscope | |||
| 4.1.1.3 | Cell specialisation | |||
| 4.1.1.4 | Cell differentiation | |||
| 4.1.1.5 | Microscopy |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.1.2.1 | Chromosomes | |||
| 4.1.2.2 | Mitosis and the cell cycle | |||
| 4.1.2.3 | Stem cells |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.1.3.1 | Diffusion; Surface area to volume ratio; Exchange surfaces | |||
| 4.1.3.2 | Osmosis | |||
| 4.1.3.3 | Active transport |
2Organisation
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.2.1 | Cells, tissues, organs and organ systems; Size and scale |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.2.2.1 | The digestive system; Enzymes; Amylase, proteases and lipases; Bile; Required practical: food tests; Required practical: the effect of pH on amylase | |||
| 4.2.2.2 | The heart and the double circulatory system; Controlling the heart rate; The lungs and gas exchange; Blood vessels | |||
| 4.2.2.3 | Blood | |||
| 4.2.2.4 | Coronary heart disease; Treating cardiovascular disease | |||
| 4.2.2.5 | Health and disease; Handling data about disease | |||
| 4.2.2.6 | Risk factors and causes; The effect of lifestyle on disease; The cost of non-communicable diseases; Using data about risk factors | |||
| 4.2.2.7 | Cancer |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.2.3.1 | Plant tissues; The leaf as an organ | |||
| 4.2.3.2 | Roots, xylem and phloem; Transpiration and stomata; Factors affecting the rate of transpiration |
3Infection and response
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.3.1.1 | Communicable (infectious) diseases | |||
| 4.3.1.2 | Viral diseases | |||
| 4.3.1.3 | Bacterial diseases | |||
| 4.3.1.4 | Fungal diseases | |||
| 4.3.1.5 | Protist diseases | |||
| 4.3.1.6 | Human defence systems | |||
| 4.3.1.7 | Vaccination | |||
| 4.3.1.8 | Antibiotics and painkillers | |||
| 4.3.1.9 | Discovery and development of drugs |
4Bioenergetics
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.4.1.1 | The photosynthetic reaction | |||
| 4.4.1.2 | Factors that affect the rate of photosynthesis; Interacting factors and the inverse square law; Required practical: light intensity and the rate of photosynthesis | |||
| 4.4.1.3 | Uses of glucose from photosynthesis |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.4.2.1 | Aerobic and anaerobic respiration | |||
| 4.4.2.2 | Response to exercise | |||
| 4.4.2.3 | Metabolism |
Biology Paper 21 hour 15 minutes · 70 marks
5Homeostasis and response
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.5.1 | What homeostasis is; Parts of a control system |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.5.2.1 | Structure and function of the nervous system; Reflex actions and the reflex arc; Required practical: reaction time |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.5.3.1 | The human endocrine system | |||
| 4.5.3.2 | Control of blood glucose concentration; Type 1 and Type 2 diabetes | |||
| 4.5.3.4 | Hormones in human reproduction | |||
| 4.5.3.5 | Contraception | |||
| 4.5.3.6 | The use of hormones to treat infertility Higher tier | |||
| 4.5.3.7 | Adrenaline, thyroxine and negative feedback Higher tier |
6Inheritance, variation and evolution
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.6.1.1 | Sexual and asexual reproduction | |||
| 4.6.1.2 | Meiosis | |||
| 4.6.1.4 | DNA and the genome | |||
| 4.6.1.6 | Genetic inheritance | |||
| 4.6.1.7 | Inherited disorders | |||
| 4.6.1.8 | Sex determination |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.6.2.1 | Variation | |||
| 4.6.2.2 | Evolution | |||
| 4.6.2.3 | Selective breeding | |||
| 4.6.2.4 | Genetic engineering |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.6.3.4 | Evidence for evolution | |||
| 4.6.3.5 | Fossils | |||
| 4.6.3.6 | Extinction | |||
| 4.6.3.7 | Resistant bacteria |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.6.4 | The Linnaean system and binomial names; Developments in classification |
7Ecology
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.7.1.1 | Communities | |||
| 4.7.1.2 | Abiotic factors | |||
| 4.7.1.3 | Biotic factors | |||
| 4.7.1.4 | Adaptations |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.7.2.1 | Producers, consumers and food chains; Sampling: distribution and abundance; Predator-prey cycles | |||
| 4.7.2.2 | How materials are cycled |
| Spec | What to know (the note) | Not yet | Nearly | Confident |
|---|---|---|---|---|
| 4.7.3.1 | Biodiversity | |||
| 4.7.3.2 | Waste management | |||
| 4.7.3.3 | Land use | |||
| 4.7.3.4 | Deforestation | |||
| 4.7.3.5 | Global warming | |||
| 4.7.3.6 | Maintaining biodiversity |
Ticks are not saved, so print the checklist to keep track. Look up any word you are unsure of in the glossary, and when a topic is green, try it on past papers.