The immune response: exam questions

8 questions, 32 marks. Write your answers on paper, then open each mark scheme.

Spec 6.8–6.12
A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean
Questions and mark scheme (PDF)5 pages

Question 1

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

Explain how inflammation helps to destroy pathogens at a site of infection.

[4 marks]
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Question 2

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

Describe how interferon and lysozyme each help to protect the body from infection.

[4 marks]
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Question 3

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

Explain why an antibody that binds to the surface of one species of bacterium does not bind to a different species.

[3 marks]
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Question 4

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

Describe the roles of B cells and T cells in the immune response to a pathogen that the body has not met before.

[6 marks]
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Question 5

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

A person was given a vaccine on day 0 and a second dose of the same vaccine on day 28. The table shows the concentration of antibody in the blood. (a) Describe the differences between the response to the first dose and the response to the second dose. (3) (b) Explain the differences you have described. (2)

Antibody concentration after vaccination
DayAntibody concentration / arbitrary units
00
72
1418
2130
2822
3595
42150
49120
[5 marks]
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Question 6

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

Compare and contrast natural passive immunity with artificial active immunity.

[4 marks]
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Question 7

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

A baby is protected from infection by antibodies in colostrum. What type of immunity is this?

  1. Natural active
  2. Natural passive
  3. Artificial active
  4. Artificial passive
[1 mark]
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Question 8

Unit 4 style

A Level only (what this means)A Level only: only in the full A Level, not the AS Level. AS Level students can skip it. What the labels mean

Explain how the way in which HIV evades the immune system supports the theory of an evolutionary race between pathogens and their hosts.

[5 marks]
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