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DNA and the genome: exam questions

5 questions, 12 marks. Write your answers on paper, then open each mark scheme.

1

What joins the two strands of a DNA molecule together?

  1. Strong covalent bonds between sugar groups
  2. Weak hydrogen bonds between bases
  3. Strong covalent bonds between phosphate groups
  4. Weak hydrogen bonds between sugar groups
[1 mark]
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Answer: B B: Weak hydrogen bonds between bases (1)

2

Describe the structure of a DNA molecule.

[3 marks]
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  • two strands coiled to form a double helix (1)
  • strands linked by complementary base pairs joined by (weak) hydrogen bonds (1)
  • made of nucleotides, each consisting of a sugar and phosphate group (1)
  • with one of four different bases attached to the sugar (1)
  • Max 3
3

A section of one strand of DNA has the base sequence A T G C C A. (a) Write the base sequence of the complementary strand. (1) (b) Name the type of bond that holds the two strands together. (1)

[2 marks]
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  • (a) T A C G G T (1)
  • (b) hydrogen (bonds) (1)
4

State what is meant by (a) the genome of an organism (1) and (b) a gene (1).

[2 marks]
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  • (a) the entire DNA of an organism (1)
  • (b) a section of a DNA molecule that codes for a specific protein (1)
5

Describe how DNA can be extracted from a strawberry.

[4 marks]
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  • mash / crush the strawberry (1)
  • add detergent (and salt) to break down cell membranes / release DNA (1)
  • filter to remove solid pieces (1)
  • add ice-cold ethanol (1)
  • DNA appears as white stringy strands / precipitate (1)
  • Max 4