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Genetics, subtopic 1 of 5Spec 3.1B–3.3

Reproduction and meiosis

Compare asexual and sexual reproduction, and explain how meiosis makes genetically different gametes.

3 sections, with a quick check at the end.

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Asexual reproductionSpec 3.1BTriple only

In asexual reproduction there is only one parent. The offspring are genetically identical to the parent, so there is no variation in the population.

Asexual reproduction: advantages and disadvantages
PointWhy it matters
AdvantageNo need to find a mateSaves time and energy. Useful when individuals are far apart.
AdvantageRapid reproductive cycleMany offspring are made quickly, so the population can grow fast.
DisadvantageNo variation in the populationAll the individuals have the same weaknesses. A new disease or a change in the environment could kill them all.

The key idea is the trade-off. Asexual reproduction is quick and needs no partner, but the lack of variation makes the population vulnerable if conditions change.

Sexual reproductionSpec 3.2BTriple only

In sexual reproduction two parents each produce gametes. The gametes fuse at fertilisation, so the offspring inherit a mixture of alleles from both parents. This produces variation in the population.

Sexual reproduction: advantages and disadvantages
PointWhy it matters
AdvantageVariation in the populationIf the environment changes or a disease appears, some individuals are likely to have characteristics that let them survive and reproduce.
DisadvantageRequirement to find a mateThis takes time and energy, and may not always be possible.

MeiosisSpec 3.3

Meiotic cell division (meiosis) is the type of cell division that makes gametes. In humans it happens in the reproductive organs.

  • One parent cell divides to produce four daughter cells.
  • Each daughter cell has half the number of chromosomes of the parent cell.
  • The daughter cells are genetically different from each other and from the parent cell.
  • The daughter cells are haploid gametes, with one set of chromosomes.

A human body cell has 46 chromosomes. Meiosis makes sperm and egg cells with 23 chromosomes each. At fertilisation the two gametes fuse and the zygote has 46 chromosomes again, with half from each parent.

Body cells and gametes
Body cell (diploid)Gamete (haploid)
Chromosomes in a human cell4623
Genetically identical to the others?Yes, if made by mitosisNo, each gamete is different
Made byMitosisMeiosis
A diploid parent cell with 4 chromosomes divides by meiosis into four genetically different haploid gametes with 2 chromosomes each; one gamete fuses with a gamete from the other parent at fertilisation to form a diploid zygote with 4 chromosomes.Tap to enlarge
Meiosis halves the chromosome number; fertilisation restores it in the zygote.

Quick check

  1. Give one advantage and one disadvantage of asexual reproduction.

    Show answer

    Advantage: no need to find a mate (or rapid reproductive cycle). Disadvantage: no variation in the population.

  2. Give one advantage and one disadvantage of sexual reproduction.

    Show answer

    Advantage: variation in the population. Disadvantage: the requirement to find a mate.

  3. How many daughter cells does one meiotic division produce?

    Show answer

    Four.

  4. How many chromosomes are in a human gamete?

    Show answer

    23, which is half the number in a body cell (46).